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---Procedencia:
Institución:IRB, Bellinzona
Contacto correo-e:santiago.gonzalez@irb.usi.ch
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PhD position: "Immunity to flu vaccine" http://www.irb.ch/infection-and-immunity

The Institute for Research in Biomedicine (http://www.irb.ch/home) provides high-level scientific education for undergraduate as well as for graduate students. The PhD program is carried out in collaboration with Swiss and foreign universities. The experimental work is carried out at IRB under the direct supervision of a Group Leader. The program includes seminars, lessons, summer courses and an annual retreat.

The laboratory of Infection and Immunity at the IRB is seeking a higly motivated PhD candidate. The aim of the project is to study the relevance of the inflammatory reaction induced by an influenza vaccine in the lymph node. The candidate will evaluate the effects that inflammation has on the previously described mechanism of capture and transport of the viral particles from the injection site to the B cell follicle (1, 2) using state-of-the-art imaging techniques such as intravital 2-photon microscopy and confocal microscopy. The deadline for the application is the 8th of June 2013.

The sucesful candidate will hold a Master degree in biology/cell biology/biochemistry or a related area and be fluent in English. Experience in FACS, cell sorting, cell imaging will be a plus.

Application should be sent to: santiago.gonzalez@irb.usi.ch

Postdoctoral Marie Curie (IEF) candidate http://www.irb.ch/infection-and-immunity

A postdoctoral candidate interested in a 2 year post-doc position via a Marie Curie Intra-European Fellowship for Career Development (IEF) is requested. The candidate researcher is asked to collaborate in writing a Marie Curie proposal (deadline 14th August 2013) to study relevant immunological questions in different vaccination models using intravital 2-photon microscopy. Further details will be available on request. 
The laboratory is located in the Institute for Research in Biomedicine (IRB) in Bellinzona (Switzerland).
The selected candidate will be a citizen from a European Union or associated countries (Swiss nationals are excluded due to grant regulations) with a good publication record. Experience in FACS, cell sorting and imaging will be consider.


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Información complementaria de la oferta:
References:

(1) SF Gonzalez, et al. 2010. Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes. Nature Immunology. 2010;11(5):427-34.
(2) SF Gonzalez, Degn S, Pitcher LA, Woodruff M, Heesters B, Carroll MC. Trafficking of B cell antigen in lymph nodes. Annual Reviews of Immunology. 2011;29:215-33.

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