[OFER-TRABEC] NAC: Postdoc position in Systems Biology

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Institución:Centre de Regulació Genòmica
Contacto correo-e:rrhh@crg.eu
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Post Description
One postdoctoral research position is available in the laboratory of Sensory Systems and Behavior led by Dr. Matthieu Louis at the Center for Genomic Regulation (Barcelona, Spain). The successful candidate will integrate our interdisciplinary team to study the neural mechanisms underlying learned orientation behaviors in the Drosophila larva as part of the European FET-Open project MINIMAL (Miniature Insect Model of Active Learning). You will take a leading role in developing an optogenetics-based paradigm
where virtual sensory realities will be created to study the neural computations underlying associative conditioning.

Further details:
MINIMAL is a research project funded by the EC Seventh Framework FET-Open. The MINIMAL consortium consists of the University of Edinburgh (UK), the Leibniz Institute for Neurobiology (Germany), the Centre for Genomic Regulation (Spain) and Brainwave Discovery (UK). The project takes biological inspiration to engineer small low-power devices that are able to learn rapidly and autonomously about
environmental contingencies, enabling prediction and adaptive anticipatory actions. With fewer than 10,000 neurons, the Drosophila larva still expresses a variety of orientation and learning behaviors, including non-trivial anticipatory actions requiring context-dependent value evaluation. Current computational learning theory cannot account for these capacities. MINIMAL aims to develop a new
foundation for understanding natural learning by developing a complete multilevel model of learning in larvae. The goals of the project are: (1) to analyze at a fine scale how larval behavior is controlled and altered by associative conditioning and to link this knowledge to agent-based models that ground learning capabilities in sensorimotor control; (2) to build one-to-one computational neural models that can be validated by exploiting the recent expansion of the Drosophila neurogenetic toolkit to gain unprecedented ability to characterize and manipulate neural circuits during unconstrained behavior; (3) to derive from these models generalizable algorithms and circuit architectures that can be used to enhance the learning and anticipatory capabilities of machines.

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Información complementaria de la oferta:
Candidate requirements
Degree: The candidate must either hold a PhD related to Neurobiology or Systems Neuroscience, or be near the completion of his/her PhD.
Experience: A strong background in programming and computational methods for the analysis of behavior will be essential for this project. A good level of comfort with instrumentation is desired.
Expertise in Drosophila and/or the functional analysis of neural circuits is preferred.
Language: Fluent in English.
Personality: Highly motivated candidate with interactive personality who shows independent work performance.
Analytical skills and critical thinking.
Conditions
Duration: 3 years
Estimated annual gross salary: A competitive salary will be provided, which will be well matched relative to the cost of living in Barcelona, and adjusted according to experience.

Application procedure
All applications must be addressed to Dr. Matthieu Louis (Informal enquiries should be made directly to matthieu.louis@crg.eu); and include a CV with a cover motivation letter and contacts of 2-3 references indicating offer reference (Ref. SB-ML-131219) in the subject line. Please submit your application to the following email address: rrhh@crg.eu

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