[OFER-TRABEC] NAC: Graduate position for a PhD in development and evo

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Bolsas de empleo:
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http://inforuvid.com/index.php?edi=2152&SEC=4
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---Procedencia:
Institución:Universitat Autonoma de Barcelona
Contacto correo-e:isaac.salazar@uab.cat
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Graduate position for a PhD in the systems biology of evolution and development: gene networks evolution

University of Helsinki and Autonomous University of Barcelona

1.Job/ project description:

The main objectives of the PhD project is to:

a) Develop mathematical models of the relationship between genetic
and phenotypic variation (or genotype-phenotype map)

b) Understand how this relationship and the patterns of phenotypic
variation possible by genetic variation in gene networks affect
evolution.

c) Develop models about the evolution of gene networks and embryonic
development in general.

A core concept of current evolutionary biology is the
genotype-phenotype (GP) map, which connects genetic variation to
phenotypic variation and to potential for evolutionary change. The
aim of the project is to develop or investigate models of the GP map
that can be related to specific biological study systems or specific
evolutionary questions investigated by the group. There is
considerable flexibility as to the exact topics, and the interests
of the candidate will be important in defining the research subjects.

These models can be abstract or linked to specific biological
systems. The biotechnology institute includes a range of
experimental biologitst working on several systems. The supervisor
of the theoretical aspects will be Dr. Salazar-Ciudad but the PhD
would include close collaboration with Jukka Jernvall group and
would include collaboration with developmental biologists,
bioinformaticians, paleontologists and other evolutionary and
systems biologists. The work may also include, optionally,
collaboration, and spending some time, in Barcelona.
The modeling can focus on gene network regulation, cell-cell
communication, cell mechanical interactions and developmental
mechanisms in general and, optionally, artifical in silico
evolution.


2. Requirements:

The applicant should be a biologists, or similar, preferably with a strong
background in either evolutionary biology, developmental biology or
theoretical biology. Some knowledge of ecology, zoology, cell and
molecular biology are also desirable.

Bioinformaticians, systems biologists or computer biologists that do
not have a degree in biology or similar similar would not be considered
(this excludes (e.g. Computer scientists, physicists
and engineers).

Programming skills or a willingness to acquire them is required.
Familiarity with GPU computing is highly desirable.

The most important requirement is a strong interest and motivation
on science, gene networks and evolution. A capacity for creative and
critical thinking is also desirable.

3. Description of the position:

The fellowship will be for a period of up to 4 years (100% research
work: no teaching involved).

The purpose of the fellowship is research training leading to the
successful completion of a PhD degree.


Salary according to Finnish PhD student salaries.


4. The application must include:

-Application letter including a statement of interests
-CV (summarizing degrees obtained, subjects included in degree and
grades, average grade)

-Application should be send to Isaac Salazar-Ciudad by email:

isaac.salazar@helsinki.fi

Foreign applicants are advised to attach an explanation of their
University's grading system. Please remember that all documents should
be in English (no official translation is required)

5. Examples of recent publications by Isaac Salazar-Ciudad group.

-Salazar-Ciudad I1, Marín-Riera M. Adaptive dynamics under
development-based genotype-phenotype maps.
Nature. 2013 May 16;497(7449):361-4.

-Salazar-Ciudad I, Jernvall J. A computational model of teeth and
the developmental origins of morphological variation. Nature. 2010
Mar 25;464(7288):583-6.


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Información complementaria de la oferta:


6. Interested candidates should check our group webpage:


http://www.biocenter.helsinki.fi/salazar/index.html

Candidates will be selected as they come.

Isaac Salazar-Ciudad: isaac.salazar@helsinki.fi

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