[OFER-TRABEC] NAC: Candidate to apply for a predoctoral fellows

------------------------
Bolsa de empleo: http://www.biocat.cat/es/bolsa-de-empleo
*************************
(c)OFER-TRABEC es un servicio ofrecido por el Centro de Comunicaciones RedIRIS
(Permitida la reproducción siempre que se cite la fuente de este Servicio).
------------------------

---Procedencia:
Institución:Institut de Biotecnologia i Biomedicina - UAB
Contacto correo-e:ignasi.roig@uab.cat
---
We are seeking highly qualified applicants to apply for a predoctoral fellowship from the FI-DGR program (AGAUR http://www10.gencat.cat/agaur_web/AppJava/catala/a_beca.jsp?categoria=predoctorals&id_beca=20701) to do the thesis in the research group in mammalian meiosis led by Dr. Ignasi Roig Institut de Biotecnologia i Biomedicina from Universitat Autònoma de Barcelona (http://grupsderecerca.uab.cat/roiglab/).

The main objective of the research group is to study the mechanisms that regulate the progression of meiotic prophase in mice and identify the proteins involved in these processes using genetic approaches (see the website and the list of references at the end of the document, for examples of the type of studies that are conducted in the group). Specifically, the applicant's thesis project will focus on understanding the function of a newly discovered ATPase, TRIP13 in meiotic prophase and in particular the role of TRIP13 in homologous recombination and chromosome axis organization. The candidate will have to use molecular biology, genetics, histology and cytology tools to describe the function of this protein in meiosis.

Candidate Requirements:
1.-Degree in Biology, Biochemistry, Genetics, Biomedical Sciences or similar, with master studies finished between 01/01/2012 and 30/09/2014.
3.-Competitive academic record, with average grade above 2.5 (scale 0-4) or 8.5 (scale 0-10).
4.-Fluent English.

We offer:
1.-Incorporation into a young and dynamic research group with international recognition and many local and international collaborations.
2.-Ability to perform stages in other research groups with high prestige.
3.-3 years fellowship, with annual brut salary from 14,400.00 to 15,600.00 Euros.

Interested send motivation letter, CV and academic records before September 1, 2014 to the attention of Ignasi Roig: ignasi.roig@uab.cat

Recent articles in the group:

1.Barchi M.*, Roig I.*, Di Giacommo M., de Roiij DG., Keeney S. and Jasin M. ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes. PLoS Genet. 2008 May 23;4(5):e1000076. (* Co-first authors).
Impact Factor= 9,352.

2.Lu WJ, Chapo J, Roig I, Abrams JM. Meiotic recombination provokes functional activation of the p53 regulatory network. Science. 2010 Jun 4;328(5983):1278-81.
Impact Factor = 31,777.

3.Roig I, Dowdle JA, Toth A, de Rooij DG, Jasin M, Keeney S. Mouse TRIP13/PCH2 is required for recombination and normal higher-order chromosome structure during meiosis. PLoS Genet. 2010 Aug 12;6(8). pii: e1001062.
Impact Factor = 9,543.

4.Daniel K, Lange J, Hached K, Fu J, Anastassiadis K, Roig I, Steward AF, Wassmann K, Jasin M, Keeney S, Toth A. Meiotic homologue alignment and its quality check are controlled by mouse Hormad1. Nature Cell Biology 2011 May; 13(5):599-610.
Impact Factor = 19,488.

5.Churchman ML, Roig I, Keeney S, Jasin M, Sherr CJ. Transient Arf expression in spermatogonia prevents p53-dependent elimination of spermatocytes during male germ cell development. PLoS Genet. 2011 Jul; 7(7): e1002157. Impact Factor = 8,694.

6.Cole F, Kauppi L, Lange J, Roig I, Wang R, Keeney S, Jasin M. Homeostatic control of recombination is implemented progressively in mouse meiosis. Nature Cell Biology 2012 Mar 4; 14(4):424-30.
Impact Factor = 20,691.

7.Pacheco S, Marcet-Ortega M, Lange J, Jasin M, Keeney S, Roig I. The ATM-signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes. Submitted.


----------------
Información complementaria de la oferta:
Ignasi Roig, Ph.D.
Dept. Cell Biology, Physiology & Immunology
Universitat Autònoma de Barcelona

Phone +34935814396
Fax +34935813357
ignasi.roig@uab.cat
http://grupsderecerca.uab.cat/roiglab/

*************************************************************************
Para darse de baja OFER-TRABEC pinche y envíe:
mailto:OFER-TRABEC-signoff-request@listserv.rediris.es
*************************************************************************